The world of medication when it comes to anxiety and depression is intense, overwhelming and changing every day. It can also be super confusing for people with anxiety, so I decided to create this post on the different types of anxiety medication.
I’ve left many doctors’ offices with a prescription featuring the name of a medication that’s going to help me feel better. Sometimes it works, sometimes it doesn’t. But to understand the types of meds that work for me, I’ve tried to learn more about them.
To help you do the same, here’s a beginner’s guide to the different anxiety medication types.
Different Types of Anxiety Medication
To help you navigate the world of anxiety meds, here’s a brief and simplified overview of the different types and which types of anxiety disorders they’re used to treat. If you want more info on anxiety meds and my experience, check out my article on navigating anxiety meds.
Selective Serotonin Reuptake Inhibitor (SSRI)
SSRIs boost serotonin, a “feel-good” brain chemical, to help improve mood and reduce anxiety. They’re widely used for anxiety and depression and tend to have fewer side effects. Examples: Lexapro, Zoloft, Paxil and Prozac. I’ve been on a few of these, I was on Prozac for years and I’m currently on a low dose of Lexapro.
Serotonin-Norepinephrine Reuptake Inhibitor (SNRI)
SNRIs increase serotonin and norepinephrine in the brain, helping with mood, anxiety, and energy levels. They’re great for people dealing with both anxiety and fatigue. Examples: Effexor, Cymbalta. I’ve been on Cymbalta and had a terrible experience so I generally prefer to stay away from SNRIs since they don’t work for me.
Benzodiazepines
Benzos are fast-acting meds that calm you down by relaxing your brain and body. They’re typically used for short-term relief of intense anxiety or panic attacks (they’re even used for sleep). They can be addictive, so they’re used carefully. Examples: Xanax, Ativan, Klonopin. I am super cautious with using Benzos but they work really well when used responsibly.
Atypical Anxiolytics
These are non-addictive anxiety meds that work more gradually. They’re good for long-term use without the sedation or dependency risk of benzos. Example: Buspar.
Beta-Blockers
Beta-blockers are typically heart meds but can help with physical anxiety symptoms like a racing heart or shaking during stressful situations (like public speaking). Examples: Inderal, Tenormin. I’ve used them a few times for exams or when going on first dates but I haven’t taken one in years.
Tricyclic Antidepressants (TCAs)
TCAs are older antidepressants that work by increasing serotonin and norepinephrine. They’re less commonly used now due to more side effects but can be effective for anxiety and panic disorders. Examples: Elavil, Anafranil.
MAOI (Monoamine Oxidase Inhibitors)
MAOIs are powerful antidepressants that boost multiple brain chemicals. They’re used less often because they require dietary restrictions and can interact with other meds. Examples: Nardil, Parnate.
Antihistamines
These are usually allergy meds but can also be used for short-term anxiety relief. They work by calming the nervous system and are non-addictive. Examples: Vistaril, Atarax.
Anticonvulsants
Originally for seizures, these are sometimes used off-label for anxiety because they help stabilize mood and reduce overactive brain signals. Example: Neurontin and Lamotrigine. I’ve had great results on Lamotrigine and it’s one of my favorite anti anxiety meds that I’ve ever been on.
Norepinephrine-Dopamine Reuptake Inhibitors
Increase norepinephrine and dopamine levels in the brain to help improve energy, focus, and mood. They’re often used for depression and sometimes off-label for anxiety.
A common example is Wellbutrin (bupropion). NDRIs tend to have fewer sexual side effects than SSRIs or SNRIs. I’ve been taking Wellbutrin for a while and am doing well on it. It’s definitely the med I’ve had the least side effects from.
NOTE: I’ve included my personal experience with these meds BUT I am not a medical professional and my experience will likely be WIDELY different from yours. Please find yourself a psychiatrist who can guide you through this process.
Overview Table of Anxiety Meds
Type of Medication | Generic Name | Brand Names | Used For |
Selective Serotonin Reuptake Inhibitors (SSRIs) | Escitalopram | Lexapro, Cipralex | GAD, Panic Disorder |
Sertraline | Zoloft, Lustral | GAD, Panic Disorder, SAD | |
Paroxetine | Paxil, Seroxat | GAD, SAD, Panic Disorder | |
Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs) | Venlafaxine | Effexor XR, Viepax | GAD, Panic Disorder, SAD |
Duloxetine | Cymbalta, Yentreve | GAD | |
Norepinephrine-Dopamine Reuptake Inhibitors (NDRIs) | Bupropion | Wellbutrin, Zyban | Depression, smoking cessation, off-label for anxiety |
Benzodiazepines | Alprazolam | Xanax, Niravam, Kalma | Acute anxiety, Panic Disorder |
Lorazepam | Ativan, Temesta | Acute anxiety, GAD | |
Clonazepam | Klonopin, Rivotril | Panic Disorder, short-term anxiety relief | |
Beta-Blockers | Propranolol | Inderal, Hemangeol, Bedranol | Performance anxiety (situational) |
Atenolol | Tenormin, Normiten | Performance anxiety | |
Tricyclic Antidepressants (TCAs) | Amitriptyline | Elavil, Endep, Tryptanol | GAD, Panic Disorder |
Clomipramine | Anafranil, Clomicalm | OCD | |
Monoamine Oxidase Inhibitors (MAOIs) | Phenelzine | Nardil | SAD, Panic Disorder |
Tranylcypromine | Parnate | SAD, Panic Disorder | |
Atypical Anxiolytics | Buspirone | Buspar | GAD |
Antihistamines | Hydroxyzine | Vistaril, Atarax | Short-term anxiety relief |
Anticonvulsants | Gabapentin | Neurontin, Gralise | Off-label for anxiety |
Lamotrigine | Lamictal | Bipolar Disorder, off-label for anxiety |
Finding Meds That Work For You
My own journey with anxiety meds has been a struggle. It’s been a lot of side effects, withdrawal, good days and bad days. Overall, taking medication has changed my life for the better. It’s the reason I’m typing this in London after having flown her alone to see my favorite band.
Medication gets a bad rap, but it does work for some people.
Once again, please remember I am not a professional, I am just sharing my own experience, if you are struggling please reach out to someone in your life whether a friend, family member or a professional. There are people who can help and you WILL find something that works for you.
Kathryn is the creator of Art of Anxiety. She was diagnosed with GAD and MDD at 16 and has been working every day to master the art of anxiety ever since. Her favorite things to do are aerial yoga and hanging out with her cats while reading a good book.